Ninety male broiler chicks (Cobb strain) of day-old age were randomly divided into six groups consisting of fifteen in each group. Group 1 was maintained as basal diet control and group 2 on lead @ 300 ppm in feed throughout 5 wks as toxic control without any treatment. Groups 3 and 4 were maintained respectively on herbal methionine @ 1.4 gm/ kg feed and Mangifera indica @ 0.1% in feed. Groups 5 and 6 were treated with lead + herbal methionine and lead + Mangifera indica, respectively for the 5 wks. The activity of AST and the concentration of serum creatinine (blood) revealed significant (P < 0.05) increase and there were histological alterations in the lead toxic control group. Treatment with herbal remedies in groups 5 and 6 resulted in a marked improvement in all the above parameters as compared to those of lead toxic control. Thus, it is concluded that herbal methionine and Mangifera indica offered protection against lead-induced organ damage in broilers.
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